Our solutions

Our products & services are tailor-made solutions, designed for customers, with high quality standards.

We provide entire package (model reconstruction and analysis) or specific analyses with existing models.

 

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Digital Organisms Reconstruction
The heart of iMEAN's technology. Digital organisms reconstruction opens your science to new horizons! We build your digital organism from the known genome sequence of your biological organism, this process is called digital reconstruction.
White biotechnology
Digital Organisms Reconstruction
The heart of iMEAN's technology. Digital organisms reconstruction opens your science to new horizons! We build your digital organism from the known genome sequence of your biological organism, this process is called digital reconstruction.
Genome-scale metabolic network reconstruction
Genome-scale metabolic network reconstruction Image

Digital cell with a metabolic network allows simulating flow of matter and energy towards physiological traits, like biomass growth, high value compounds production, etc… under environmental constrains.

We reconstruct a high-quality large scale or genome-scale metabolic network of your organism. Each component of the network is manually curated and the model includes state-of-the-art bibliography. We run validation steps with available experimental datasets.

Regulatory network reconstruction
Regulatory network reconstruction Image

We reconstruct a high-quality large scale or genome-scale regulatory network of your organism.

Each component of the network is manually curated and the model includes state-of-the-art bibliography. We run validation steps with available experimental datasets.

White biotechnology
Synthetic Biology Design
Synthetic Biology Design Image

Get our flyer

We developed an artificial intelligence algorithm (that we call the tracker) to design synthetic organisms.

Our algorithm takes into account environmental clues, the robustness of the solution and trade-offs with other biological functions.

The strength of this approach is the combination of our high-quality curated database with the tracker that allows us to identify optimal solutions.

As compared to classical synthetic microorganism production, our virtual screen approach allows you to :

  • Simulate millions of synthetic organisms.
  • Select a limited number of synthetic organisms to validate experimentally.
  • Generate patentable synthetic solutions.

You can easily save time and money and keep a competitive edge over your competitors.

 

Green biotechnology
Crop virtual selection
Crop virtual selection Image

Get our flyer

Prediction of crops complex traits is a main challenge during seed breeding processes.

Our solution @iMEAN mixes systems biology, an approach taking into account causal biological mechanisms driving complex traits, with a genomic selection model.

Depending of your objectives, our algorithm can optimise yield, pathogen resistance, robustness to environmental variations.

Synthetic Microbiota Design
Synthetic Microbiota Design Image

We design synthetic microbiota (mixture of microbes to seed into soil or leaves) considering crop traits to be optimised and environnemental clues. Divers traits can be optimised like pathogens control efficiency, plant health and yield.

Data analyses
We analyze your data in order to make sense of it
GWAS
Omics data analysis
Omics data valuation
Omics data valuation Image

The revolution of Omics data production is leading biology in the big data era. Our technology allows making your data useful.

The analysis consists on integrating your Omics datasets into digital organisms. Combining Omics data and systems biology allows to reveal Omics to phenotype causality and  identify key drivers of the phenotype in your Omics data set.

Genomic selection
Network inference
Network inference Image

Our algorithm identifies molecular networks through a broad range of datasets, like omics data.

 

Emergente properties analysis
Emergente properties analysis Image

Many behaviors of living organisms rise at the network scale. Such so call emergent properties are complex to understand.

Our digital organisms technology allows to reveal molecular mechanisms driving emergent properties.

Among them, we performed

  • trade-off (resources allocation, crosstalk) analysis between broad set of biological functions and identify key components controlling or responsible for the trade-off.
  • robustness analysis of your organism when facing internal (mutations, chemicals) perturbations or environmental perturbations (changes in environmental conditions).
Digital Organisms Reconstruction
The heart of iMEAN's technology. Digital organisms reconstruction opens your science to new horizons! We build your digital organism from the known genome sequence of your biological organism, this process is called digital reconstruction.
Genome-scale metabolic network reconstruction Image
Genome-scale metabolic network reconstruction
Digital cell with a metabolic network allows simulating flow of matter and energy towards physiological traits, like biomass growth, high value compounds production, etc… under environmental constrains. We reconstruct a high-qua... Read More
Regulatory network reconstruction Image
Regulatory network reconstruction
We reconstruct a high-quality large scale or genome-scale regulatory network of your organism. Each component of the network is manually curated and the model includes state-of-the-art bibliography. We run validation steps with av... Read More
White biotechnology
Synthetic Biology Design Image
Synthetic Biology Design
Get our flyer We developed an artificial intelligence algorithm (that we call the tracker) to des... Read More
Green biotechnology
Crop virtual selection Image
Crop virtual selection
Get our flyer Prediction of crops complex traits is a main challenge during seed breeding processes.... Read More
Synthetic Microbiota Design Image
Synthetic Microbiota Design
We design synthetic microbiota (mixture of microbes to seed into soil or leaves) considering crop traits to be optimised and environnemental clues. Divers traits can ... Read More
Data analyses
We analyze your data in order to make sense of it
Omics data valuation Image
Omics data valuation
The revolution of Omics data production is leading biology in the big data era. Our technology allows making your data useful. The analysis consists on integrating your Omics datasets into digital organisms. Combi... Read More
Network inference Image
Network inference
Our algorithm identifies molecular networks through a broad range of datasets, like omics data.  
Emergente properties analysis Image
Emergente properties analysis
Many behaviors of living organisms rise at the network scale. Such so call emergent properties are complex to understand. Our digital organisms technology allows to reveal molecular mechanisms driving emergent properties. ... Read More

 

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